Doctor's Best, Benfotiamine 150mg with BenfoPure
120 Veggie Caps, 100% Vegetarian,
Made in USA
What is Benfotiamine?
Benfotiamine (S-benzoylthiamine-O-monophosphate) is a derivative of thiamin, belonging
to the family of compounds known as "allithiamines." Benfotiamine is fat-soluble and
more bioavailable and physiologically active than thiamin. Benfotiamine raises the blood
level of thiamin pyrophosphate (TPP), the biologically active co-enzyme of thiamin, and
stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose
Helps maintain healthy cells in the presence of blood glucose
Helps control formation of Advanced Glycation End products (AGEs)
Helps normalize cellular processes fueled by glucose metabolites
Benefits of Benfotiamine
High blood pressure
Sometimes people develop high blood pressure as a result of a phenomenon known
as baroreflex dysfunction. There are nerves that control the valves that hold blood in
place when you stand up and that release the blood when you sit or lie down.
If these nerves are damaged (usually by poorly controlled diabetes), you can effectively
have high blood pressure when you stand up or while you are seated, and low blood
pressure when you lie down. Or you might have high blood pressure in one arm and
normal blood pressure in the other. Treatment with benfotiamine helps restore nerve
function to control these valves and sometimes produces dramatic improvements in
high blood pressure even without medication.
Benfotiamine for Alcoholic Neuropathy
People who are alcoholics or who drink heavily often develop vitamin B1 deficiencies.
The first sign of chronic B1 deficiency may be tingling in the fingers and toes. The tingling
may be followed by burning and then numbness, and then numbness may be followed
by inability to use the hands and a tendency to fall even without becoming intoxicated
because of lack of feeling in the feet. Benfotiamine is especially helpful in treating
Maintains a Healthy Metabolism
Benfothiamine is needed to make adenosine triphosphate (ATP), the body’s main
energy-carrying molecule, within the mitochondria of cells. Thiamine helps in the
conversion of carbohydrates into glucose, which is the preferred source of energy
that the body runs off of to keep your metabolism running smoothly. Thiamine also
helps break down proteins and fats too (4). We know that the coenzymatic form of
thiamine is involved in two main types of metabolic reactions within the body:
decarboxylation and transketolation. After eating something containing thiamine, it
is transported in theblood and plasma and then used by the cells to convert energy.
Prevents Nerve Damage
Benfothiamine is needed to convert carbohydrates from our food, and the main role of
carbohydrates is to provide energy for the body, especially for the brain and nervous
system. Thiamine is specifically needed for a system of enzyme reactions called
pyruvate dehydrogenase, which works to oxidize sugars that we eat. Without enough
“fuel” from food going towards the function of our nervous system, we can experience
nerve damage that can result in trouble moving, learning, and remembering information.
Benfothiamine also helps with proper development of myelin sheaths, which wrap
around nerves to protect them from damage and death.
Prevents Brain Disorders
Thiamine helps to bridge the gap between the brain/body connection. It can help defend
against a type of brain damage called cerebellar syndrome. Healthcare providers will
also sometimes give high doses of thiamine to patients to prevent certain memory
disorders that are commonly seen in thiamine deficient people, including those
experiencing alcohol withdrawal or coming out of a coma (8). It is also linked with
decreasing the risk of Alzheimer’s disease.
Benfothiamine is a crucial vitamin for increasing focus, energy, fighting chronic stress,
and possibly preventing memory loss. Studies have linked thiamine deficiency to
problems learning and retaining information. One study showed that Benfothiamine
caused quick reaction times and feelings of clear-headedness in those taking tests.
Serving Size 1 capsule
Servings Per Container 120 servings
Amount per serving
% Daily Value
† Daily Value not established.
Adult Use: Take 1 capsule daily, with or without food, or as recommended by a
Modified cellulose (vegetarian capsule), microcrystalline cellulose, silicon dioxide.
Non-GMO / gluten free / vegan
Store in a cool dry place.